iLab Organizer :: Human Immune Monitoring Center (2024)

Welcome to the HIMC - Human Immune Monitoring Center

Quick Menu:

  • Overview of Services
  • Getting Started Help
  • Publication Acknowledgement
  • Price List

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Overview of Services

The Human Immune Monitoring Center (HIMC) is designed to be a comprehensive source for immune monitoring services for clinical and translational studies. We perform:

Immunoassays: Luminexand Olink Target-96 platforms

Mass Cytometry (CyTOF): Immunophenotyping, Intracellular cytokines, Phospho-epitopes

Flow Cytometry: Immunophenotyping,Intracellular cytokines, Phospho-epitopes

Genomics: RNA/DNA extractions, Microfluidic qPCR arrays, single-cellRNAseq

Goals of the HIMC include:

  1. To provide standardized, state-of-the art immune monitoring assays at the RNA, protein, and cellular level. These are assays that have already been validated in the HIMC.
  2. To test and develop new technologies for immune monitoring. We are always developing new assays in the above areas, as well as testing new potential immune monitoring platforms.
  3. To efficiently archive, report, and mine data from immune monitoring studies, so as to increase the value of the data and to assist in biomarker discovery. The HIMC uses Stanford Data Miner for integration of data from the standard HIMC assays, along with de-identified clinical and demographic data. One year after release of results to an investigator, data will be released for all users of the HIMC to access, unless appealed by the investigator for reasons of still-pending publication.

The HIMC was developed in 2007 by the Institute for Immunity, Transplantation, and Infection (Mark Davis, Ph.D., director) in conjunction with the Center for Clinical Immunology (C. Garrison Fathman, founder). Our Faculty Advisor is Mark Davis.

Getting Started

  • Stanford Users: LOGINorREGISTERfor an iLab account using validStanford credentials (SUNet ID).
  • Non-Stanford Users: ClicktoLOGINwith approvediLab credentials.Or,click to SIGN UPfor an iLab account. Brief instructions to get you started:

All Non-StanfordCustomers - Getting a Project Quote

Please register for an iLab account so that we can generate a quote for your project.

To get started with iLab: Go to http://sharedfacilities.stanford.edu to register for an iLab account. Click the blue sign-up button in the upper right corner. After you click submit, iLab Support will send you your login credentials.

Once logged in, click on 'list all cores' on the left side of your page. Locate the Human Immune Monitoring Center, then open the Request Services tab.

To set up your project and receive a quote for services:Request Services from the “External Users” > “initiate request” button.

There are two forms to complete…

  1. The User (Service) Agreement form (download, then upload the signed agreement). This is our standard user service agreement and must be in place before we can begin any work. If you are just requesting a quote for a Grant Proposal, you may upload the form unsigned.

Please be sure to click “save completed form”

2. Complete the HIMC Service Request Form to select from our menu of services.

Select services from the menus (enter the anticipated number of samples) then click “Add selected services” to save the selections to the form.

When done completing the form, click “submit completed form” (at the bottom of the page) to save the entire form.

Once the form is submitted, we will be able to see your project in iLab and can generate a quote for your request.

Confirming Your Project is a GO!

When you've agreed to the services listed and require no more edits from us, and you want to move forward with the work, please click the Researcher Agree button.

  1. Our Standard Service Agreement will need to be signed
  2. We require a company Purchase Order from your company before we can begin work.

Please let us know if you have any questions.

Thank you, and we look forward to working with you!

Leadership

Holden Maecker, PhD | Facility Director

Office (Rm D039, Fairchild Building): (650) 723-1671

Email: maecker at stanford.edu

Staff

Name

Role

Phone

Email

Location

Iris Herschmann

Immunoassay Specialist

650-723-4984

irish2@stanford.edu

1651 Page Mill Road, Palo Alto, CA 94304; Rm 360

Mike Leipold

Mass Cytometry (CyTOF) Manager

650-723-4984

mleipold@stanford.edu

299 Campus Dr. Fairchild Science Bldg; Rm D033

Xuhuai JiGenomics Manager650-723-5050xuhuai.ji@stanford.edu

1651 Page Mill Road, Palo Alto, CA 94304; Rm 107

Locations and Hours of Operation

Location

Building

Room

Hours

Location

Immunoassay & Cell Analysis Lab

1651 Page Mill Road,

360

9 AM - 5 PM

Genomics Lab

1651 Page Mill Road,

107

9AM - 5 PM

Mass Cytometry & Flow

299 Campus Dr. Fairchild Sci Bldg

D033

9 AM - 5 PM

http://goo.gl/maps/swj8g

Links and Resources

Publication Acknowledgement

As with all Stanford Service Centers, credit must be given to Human Immune Monitoring Center (HIMC) for data that results in a publication. If the work done at HIMC produces data resulting in a figure in a publication, you are required to acknowledge HIMC in the publication. Further, if HIMC staff members provided significant experimental design, data interpretation, or other intellectual contribution (as evaluated by the PI), then it is expected that these individuals will be coauthors on the publication.

One of our CyTOFs was purchased with funds from a NIH S10 Shared Instrumentation Grant (S10RR027431-01). Please acknowledge this grant in your papers using CyTOF data.

Return to Top

Contacts

Name Role Phone Email Location
Holden Maecker, PhD

Director

650.723.1671

maecker@stanford.edu

Fairchild Sci Bldg, Rm D039, 299 Campus Drive, Stanford, California 94305-5124

Debra Panasuk

Finance Operations

650.725.7483

dpanasuk@stanford.edu

Biomedical Innovations Building, 240 Pasteur Dr., Palo Alto, CA 94304-5422


Service Price List


Search available services:View: by categoryalphabetically

Flow Cytometry (10)
Immuno Assays (8)
Molecular and Genomic Assays (16)
Other Services and Fees (1)

Map



View HIMC Locations in a larger map

iLab Organizer :: Human Immune Monitoring Center (2024)

FAQs

What is immune monitoring? ›

Immuno-oncology and evaluation of immunotherapy

During immunotherapy research protocols, immune monitoring allows the evaluation of the reactivity of immune responses at the populational and single-cell level.

What is human immune system information? ›

The immune system is a complex network of organs, cells and proteins that defends the body against infection, whilst protecting the body's own cells. The immune system keeps a record of every germ (microbe) it has ever defeated so it can recognise and destroy the microbe quickly if it enters the body again.

How do you check if your immune system is bad? ›

Blood tests can determine if you have typical levels of infection-fighting proteins (immunoglobulins) in your blood and measure the levels of blood cells and immune system cells.

How do I check my immune status? ›

You can test for the presence or level of an antibody in blood using a serology test. The test can show whether your body could protect you from getting an infection or from getting severe disease symptoms.

What are the symptoms of low immune system? ›

Frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections. Inflammation and infection of internal organs. Blood disorders, such as low platelet count or anemia. Digestive problems, such as cramping, loss of appetite, nausea and diarrhea.

What are signs that your immune system is fighting a virus? ›

Signs Your Body Is Fighting a Cold
  • Body aches.
  • Congestion.
  • Cough.
  • Decreased appetite.
  • Fatigue.
  • Feeling rundown or unwell.
  • Mild headache.
  • Low-grade fever (99 F to 100.3 F)

What is the best way to monitor the immune system? ›

Tools for immune monitoring research
  1. Flow cytometry. Cell surface markers are regularly used for monitoring the heterogeneity of subsets of cells. ...
  2. Immunohistochemistry. ...
  3. Single-cell multiomics.

What does the immune system detect? ›

The main job of the innate immune system is to fight harmful substances and germs that enter the body, for instance through the skin or digestive system. The adaptive (specific) immune system makes antibodies and uses them to specifically fight certain germs that the body has previously come into contact with.

What is the main function of immune surveillance? ›

The mechanisms used by the host to mount a response against any antigens that are expressed by a neoplasm are called immunosurveillance. The primary function of the immune system is to recognize and degrade foreign (non-self) antigens in the body that arise de novo or are inflicted on the host.

What is an immunity screening test? ›

Antibody serology tests can show that you have an immune response to a pathogen. But they cannot show if you have full protection from a disease or how long the protection lasts. In the case of a newer disease like COVID-19, it is not yet known how long protection lasts after being infected or vaccinated.

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