The Sleep Heart Health Study: Design, rationale, and methods (2024)

Abstract

The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate obstructive sleep apnea (OSA) and other sleep- disordered breathing (SDB) as risk factors for the development of cardiovascular disease. The study is designed to enroll 6,600 adult participants aged 40 years and older who will undergo a home polysomnogram to assess the presence of OSA and other SDB. Participants in SHHS have been recruited from cohort studies in progress. Therefore, SHHS adds the assessment of OSA to the protocols of these studies and will use already collected data on the principal risk factors for cardiovascular disease as well as follow-up and outcome information pertaining to cardiovascular disease. Parent cohort studies and recruitment targets for these cohorts are the following: Atherosclerosis Risk in Communities Study (1,750 participants), Cardiovascular Health Study (1,350 participants), Framingham Heart Study (1,000 participants), Strong Heart Study (600 participants), New York Hypertension Cohorts (1,000 participants), and Tucson Epidemiologic Study of Airways Obstructive Diseases and the Health and Environment Study (900 participants). As part of the parent study follow-up procedures, participants will be surveyed at periodic intervals for the incidence and recurrence of cardiovascular disease events. The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke.

Original languageEnglish (US)
Pages (from-to)1077-1085
Number of pages9
JournalSleep
Volume20
Issue number12
StatePublished - 1997

Keywords

  • Cardiovascular disease
  • Epidemiology
  • Risk factors
  • Sleep apnea

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology (medical)

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Quan, S. F., Howard, B. V., Iber, C., Kiley, J. P., Nieto, F. J., O'Connor, G. T., Rapoport, D. M., Redline, S., Robbins, J., Samet, J. M., & Wahl, P. W. (1997). The Sleep Heart Health Study: Design, rationale, and methods. Sleep, 20(12), 1077-1085.

The Sleep Heart Health Study: Design, rationale, and methods. / Quan, Stuart F.; Howard, Barbara V.; Iber, Conrad et al.
In: Sleep, Vol. 20, No. 12, 1997, p. 1077-1085.

Research output: Contribution to journalArticlepeer-review

Quan, SF, Howard, BV, Iber, C, Kiley, JP, Nieto, FJ, O'Connor, GT, Rapoport, DM, Redline, S, Robbins, J, Samet, JM & Wahl, PW 1997, 'The Sleep Heart Health Study: Design, rationale, and methods', Sleep, vol. 20, no. 12, pp. 1077-1085.

Quan SF, Howard BV, Iber C, Kiley JP, Nieto FJ, O'Connor GT et al. The Sleep Heart Health Study: Design, rationale, and methods. Sleep. 1997;20(12):1077-1085.

Quan, Stuart F. ; Howard, Barbara V. ; Iber, Conrad et al. / The Sleep Heart Health Study : Design, rationale, and methods. In: Sleep. 1997 ; Vol. 20, No. 12. pp. 1077-1085.

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title = "The Sleep Heart Health Study: Design, rationale, and methods",

abstract = "The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate obstructive sleep apnea (OSA) and other sleep- disordered breathing (SDB) as risk factors for the development of cardiovascular disease. The study is designed to enroll 6,600 adult participants aged 40 years and older who will undergo a home polysomnogram to assess the presence of OSA and other SDB. Participants in SHHS have been recruited from cohort studies in progress. Therefore, SHHS adds the assessment of OSA to the protocols of these studies and will use already collected data on the principal risk factors for cardiovascular disease as well as follow-up and outcome information pertaining to cardiovascular disease. Parent cohort studies and recruitment targets for these cohorts are the following: Atherosclerosis Risk in Communities Study (1,750 participants), Cardiovascular Health Study (1,350 participants), Framingham Heart Study (1,000 participants), Strong Heart Study (600 participants), New York Hypertension Cohorts (1,000 participants), and Tucson Epidemiologic Study of Airways Obstructive Diseases and the Health and Environment Study (900 participants). As part of the parent study follow-up procedures, participants will be surveyed at periodic intervals for the incidence and recurrence of cardiovascular disease events. The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke.",

keywords = "Cardiovascular disease, Epidemiology, Risk factors, Sleep apnea",

author = "Quan, {Stuart F.} and Howard, {Barbara V.} and Conrad Iber and Kiley, {James P.} and Nieto, {F. Javier} and O'Connor, {George T.} and Rapoport, {David M.} and Susan Redline and John Robbins and Samet, {Jonathan M.} and Wahl, {Patricia W.}",

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AU - Iber, Conrad

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AU - O'Connor, George T.

AU - Rapoport, David M.

AU - Redline, Susan

AU - Robbins, John

AU - Samet, Jonathan M.

AU - Wahl, Patricia W.

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AB - The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate obstructive sleep apnea (OSA) and other sleep- disordered breathing (SDB) as risk factors for the development of cardiovascular disease. The study is designed to enroll 6,600 adult participants aged 40 years and older who will undergo a home polysomnogram to assess the presence of OSA and other SDB. Participants in SHHS have been recruited from cohort studies in progress. Therefore, SHHS adds the assessment of OSA to the protocols of these studies and will use already collected data on the principal risk factors for cardiovascular disease as well as follow-up and outcome information pertaining to cardiovascular disease. Parent cohort studies and recruitment targets for these cohorts are the following: Atherosclerosis Risk in Communities Study (1,750 participants), Cardiovascular Health Study (1,350 participants), Framingham Heart Study (1,000 participants), Strong Heart Study (600 participants), New York Hypertension Cohorts (1,000 participants), and Tucson Epidemiologic Study of Airways Obstructive Diseases and the Health and Environment Study (900 participants). As part of the parent study follow-up procedures, participants will be surveyed at periodic intervals for the incidence and recurrence of cardiovascular disease events. The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke.

KW - Cardiovascular disease

KW - Epidemiology

KW - Risk factors

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The Sleep Heart Health Study: Design, rationale, and methods (2024)

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